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KMID : 0363220080460081087
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Korean Journal of Dermatology
2008 Volume.46 No. 8 p.1087 ~ p.1089
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A Case of Eccrine Spiradenoma in a Neurofibromatosis Type-1 Patient
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Choi Ji-Hoon
Park Chang-Keun
Kim Hye-One
Park Cheon-Wook
Lee Cheol-Heon
Lee Hee-Bong
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Abstract
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Eccrine spiradenoma is a rare benign tumor which is differentiated into the direction of eccrine gland. Neurofibromatosis type-1 is an autosomal dominantly inherited disorder that is characterized by neurofibroma, caf? au lait spots and axillary freckles of the skin. We report a case of a 42-year-old man with a painful, solid nodule on his right arm for 4~5 months. He was diagnosed with neurofibromatosis type-1 in childhood. He has several cafe au lait spots and diffuse freckles on whole body. On microscopy, the tumor was sharply demarcated with encapsulated lobules in the dermis. The lobules consisted of two undifferentiated epithelial cells. There was hyperpigmentation of the basal cell layer in the epidermis without increase in the number of melanocyte. We herein report an unusual case of eccrine spiradenoma in neurofibromatosis type-1 patient.
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KEYWORD
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Eccrine spiradenoma, Neurofibromatosis Type-1
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